Dynamics of interleukin-17 in patients with multiple sclerosis and two-phase model of disease patho-genesis

Objective. To study the concentration of pro-inflammatory cytokine interleukin-17 in blood serum patients with multiple sclerosis.
 Materials and methods. 68 sclerosis were examined. The severity neurological deficit was assessed by EDSS MSFC. determined method enzyme-linked immunosorbent assay.
 Results. It found that sclerosis, serum, normal group as a whole, induced effect immunomodulatory therapy well decrease activity inflammatory processes an increase duration disease.
 Conclusions. MDDMS is most effective early stages disease; later stages, activities associated neurotrophic support play special role.